地西泮联合缩宫素治疗对于潜伏期延长产妇妊娠结局与睡眠质量的影响分析(1)
摘要 目的：应用地西泮和缩宫素联合治疗对潜伏期延长产妇的妊娠结局和睡眠质量的影响。方法：选取2017年1月至2019年2月山东省肥城市人民医院收治的潜伏期延长产妇76例作为研究对象，按照随机数字表法分为对照组和观察组，每组38例。对照组产妇接受静脉注射缩宫素，观察组产妇接受地西泮和缩宫素联合治疗。结果：对照组不良妊娠结局发生率为23.7%，高于观察组的不良妊娠结局发生率为5.2%;治疗后的观察组产妇睡眠质量评分优于对照组，差异有统计学意义(P<0.05)。结论：应用缩宫素和地西泮联合治疗潜伏期延长产妇可有效改善妊娠结局，提高产妇的睡眠质量，效果显著，值得推广。
关键词 地西泮;缩宫素;联合治疗;潜伏期延长;产妇;妊娠结局;睡眠质量;影响
Effect of Diazepam Combined with Oxytocin on Maternal Pregnancy Outcome and Sleep Quality
SHI Fengli
(Department of Gynecology and Obstetrics，Feicheng people′s Hospital，Feicheng 271600，China)
Abstract Objective：To compare the effects of diazepam and oxytocin on the pregnancy outcome and sleep quality of women with latent period.Methods：A total of 76 patients with latent period extension were enrolled in our hospital from January 2017 to February 2019.They were randomly divided into control group and observation group，with 38 cases in each group.The control group received the intravenous oxytocin，while the observation group received a combination of diazepam and oxytocin.Results：The incidence of adverse pregnancy outcome in the control group was 23.7%，which was higher than that in the observation group(5.2%).The postoperative quality of the maternal sleep quality score was better than that of the control group(P<0.05).Conclusion：The combination of oxytocin and diazepam in the treatment of latent women can effectively improve the pregnancy outcome and improve the quality of maternal sleep.The effect is significant and worth promoting.
Keywords Diazepam; Oxytocin; Combination therapy; Prolonged latency; Maternal; Pregnancy outcome; Sleep quality
中图分类号：R714;R338.63文献标识码：Adoi：10.3969/j.issn.2095-7130.2020.04.030
经由阴道分娩的过程中，部分孕妇会产生焦虑、紧张和恐惧等消极心理，由于过度紧张而引起宫颈痉挛或者水肿情况，从而延长产程。潜伏期延长极易导致产妇出现难产，对妊娠结局产生不利影响，因此如何对潜伏期延长进行预防和处理成为了关键问题[1]。本次研究应用地西泮和缩宫素联合治疗对潜伏期延长产妇的妊娠结局和睡眠质量的影响，现将结果报道如下。
1 资料与方法
1.1 一般资料 选取2017年1月至2019年2月山东省肥城市人民医院收治的潜伏期延长产妇76例作为研究对象，按照随机数字表法分为对照组和观察组，每组38例。对照組中年龄24～35岁，平均年龄(30.26±3.77)岁;孕周37～41周，平均孕周(39.26±0.42)周。观察组中年龄22～34岁，平均年龄(29.49±3.84)岁;孕周37～40周，平均孕周(38.81±0.23)周。2组患者一般资料经比较，差异无统计学意义(P>0.05)，具有可比性。
1.2 治疗方法 对照组产妇接受静脉注射缩宫素，根据产妇的具体情况合理选择缩宫素的用药量[1]。观察组产妇接受地西泮和缩宫素进行联合治疗，先对产妇注射地西泮，产妇的精神状态由焦虑、不安和紧张转变为积极心态，最终进入稳定的睡眠状态。直至产妇休息30 min之后再对产妇采取静脉注射缩宫素和葡萄糖混合液，浓度分别为2.5 U和50 g/L，葡萄糖注射液的用量为500 mg，将混合液以9滴/min的速度对产妇进行滴注，实时监测产妇的身体体征变化情况，根据产妇的宫缩情况和胎儿的状况对滴注速度进行合理调整，最高不可超过40滴/min[2]。
1.3 观察指标 根据匹兹堡睡眠质量指数的标准，评估并比较2组产妇的睡眠质量，同时比较2组产妇的妊娠结局。匹兹堡睡眠质量指数的总分为21分，分值≤7分时表明睡眠质量好，分值>7分表明睡眠质量差[3]。, 百拇医药(石风丽)
关键词 地西泮;缩宫素;联合治疗;潜伏期延长;产妇;妊娠结局;睡眠质量;影响
Effect of Diazepam Combined with Oxytocin on Maternal Pregnancy Outcome and Sleep Quality
SHI Fengli
(Department of Gynecology and Obstetrics，Feicheng people′s Hospital，Feicheng 271600，China)
Abstract Objective：To compare the effects of diazepam and oxytocin on the pregnancy outcome and sleep quality of women with latent period.Methods：A total of 76 patients with latent period extension were enrolled in our hospital from January 2017 to February 2019.They were randomly divided into control group and observation group，with 38 cases in each group.The control group received the intravenous oxytocin，while the observation group received a combination of diazepam and oxytocin.Results：The incidence of adverse pregnancy outcome in the control group was 23.7%，which was higher than that in the observation group(5.2%).The postoperative quality of the maternal sleep quality score was better than that of the control group(P<0.05).Conclusion：The combination of oxytocin and diazepam in the treatment of latent women can effectively improve the pregnancy outcome and improve the quality of maternal sleep.The effect is significant and worth promoting.
Keywords Diazepam; Oxytocin; Combination therapy; Prolonged latency; Maternal; Pregnancy outcome; Sleep quality
中图分类号：R714;R338.63文献标识码：Adoi：10.3969/j.issn.2095-7130.2020.04.030
经由阴道分娩的过程中，部分孕妇会产生焦虑、紧张和恐惧等消极心理，由于过度紧张而引起宫颈痉挛或者水肿情况，从而延长产程。潜伏期延长极易导致产妇出现难产，对妊娠结局产生不利影响，因此如何对潜伏期延长进行预防和处理成为了关键问题[1]。本次研究应用地西泮和缩宫素联合治疗对潜伏期延长产妇的妊娠结局和睡眠质量的影响，现将结果报道如下。
1 资料与方法
1.1 一般资料 选取2017年1月至2019年2月山东省肥城市人民医院收治的潜伏期延长产妇76例作为研究对象，按照随机数字表法分为对照组和观察组，每组38例。对照組中年龄24～35岁，平均年龄(30.26±3.77)岁;孕周37～41周，平均孕周(39.26±0.42)周。观察组中年龄22～34岁，平均年龄(29.49±3.84)岁;孕周37～40周，平均孕周(38.81±0.23)周。2组患者一般资料经比较，差异无统计学意义(P>0.05)，具有可比性。
1.2 治疗方法 对照组产妇接受静脉注射缩宫素，根据产妇的具体情况合理选择缩宫素的用药量[1]。观察组产妇接受地西泮和缩宫素进行联合治疗，先对产妇注射地西泮，产妇的精神状态由焦虑、不安和紧张转变为积极心态，最终进入稳定的睡眠状态。直至产妇休息30 min之后再对产妇采取静脉注射缩宫素和葡萄糖混合液，浓度分别为2.5 U和50 g/L，葡萄糖注射液的用量为500 mg，将混合液以9滴/min的速度对产妇进行滴注，实时监测产妇的身体体征变化情况，根据产妇的宫缩情况和胎儿的状况对滴注速度进行合理调整，最高不可超过40滴/min[2]。
1.3 观察指标 根据匹兹堡睡眠质量指数的标准，评估并比较2组产妇的睡眠质量，同时比较2组产妇的妊娠结局。匹兹堡睡眠质量指数的总分为21分，分值≤7分时表明睡眠质量好，分值>7分表明睡眠质量差[3]。, 百拇医药(石风丽)
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