黄梦朦，南克，韩园，邵玲笑，胡梦洁，南洋，姬斌，林函，李军

    (温州医科大学附属第二医院育英儿童医院 麻醉与围术期医学科，浙江 温州 325027)

    单次短时七氟烷全身麻醉对0～3岁儿童术后早期智能发育的影响

    黄梦朦，南克，韩园，邵玲笑，胡梦洁，南洋，姬斌，林函，李军

    (温州医科大学附属第二医院育英儿童医院 麻醉与围术期医学科，浙江 温州 325027)

    目的：探讨单次短时七氟烷全身麻醉对0～3岁儿童术后早期智能发育的影响。方法：采用Gesell发育量表对200例0～3岁儿童进行麻醉前1 d与麻醉后3个月发育情况的评测与对比；再分别选取与麻醉前1 d和麻醉后3个月同龄的正常儿童各200例为对照组I和对照组I I。结果：与麻醉前1 d相比较，麻醉后3个月儿童的4个能区发育龄均有不同程度提高(P<0.001)；麻醉前后各能区的发育商数(DQ)差异均无统计学意义(P>0.05)。与对照组同龄儿童比较，麻醉前1 d及麻醉后3个月各能区DQ差异均无统计学意义(P>0.05)。结论：接受单次短时七氟烷全身麻醉对0～3岁儿童术后Gesell发育量表各指标没有明显影响，各能区随着年龄发育均正常。

    麻醉，全身；Gesell发育量表；智能发育

    Abstract: Objective:To explore the effect of single short-term sevoflurane general anesthesia on early postoperative intelligence development in children aged 0-3 years.Methods:Gesell development scale was used to evaluate the neurological development (DQ) of 200 children aged 0 to 3 years old 1 day preoperatively and 3 months after operation. Another 200 normal children in the same age range were selected respectively as control group I and control group II which compared and contrasted with those in anesthesia group.Results:Compared with the DQ scores preoperative 1 day, the developmental age (motor, adaptive, verbal, social) of the four energy regions of children increased to varying degrees after 3 months of anesthesia (P<0.001). The difference of DQ scores of four energy regions 1 day preoperatively and 3 months after operation was not statistically significant(P>0.05). There was no significant difference in DQ scores of four energy regions between anesthesia group and control group (P>0.05).Conclusion:A single short-term sevoflurane general anesthesia has no significant effect on the postoperative DQ of Gesell development scales in children aged 0-3 years, and all energy regions are normal development with age. ......