阿司匹林缓释微球的制备及其体内外释放规律的研究(1)
【摘 要】目的：制备阿司匹林缓释微球并研究其体内外释放规律。方法：采用乳化溶剂挥发法制备阿司匹林缓释微球，采用动态透析法测定其体外释放度，通过大鼠药动学实验研究其体内释药规律。结果：制备的缓释微球圆整光滑，粒径分布均匀，平均载药量为51.6%，平均包封率为89.4%，最大吸收浓度为0.344ug/ml，平均滞留时间为228.12h，体内外相关性良好。结论：微球在大鼠体内有明显的缓释作用，可在较长时间内维持一定的血药浓度，达到了预期的目的。
【关键词】阿司匹林；缓释微球；乳化溶剂挥发法；药动学
Study on the preparation of aspirin sustained release microspheres and the release law of the body and the body
Abstract Objective：to prepare aspirin sustained-release microspheres and study its internal and external release.Methods：the emulsion solvent evaporation method preparation of aspirin sustained-release microspheres ......
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【关键词】阿司匹林；缓释微球；乳化溶剂挥发法；药动学
Study on the preparation of aspirin sustained release microspheres and the release law of the body and the body
Abstract Objective：to prepare aspirin sustained-release microspheres and study its internal and external release.Methods：the emulsion solvent evaporation method preparation of aspirin sustained-release microspheres ......
您现在查看是摘要页，全文长 3006 字符。