【摘 要】目的：探讨弥散加权成像(DWI)与MR波谱成像(MRS)联合应用对前列腺癌的检出率和临床意义。方法：通过回顾性分析经穿刺病理证实为前列腺癌的120例病人在前列腺切除术前的DWI及MRS表现，发现、定位并诊断前列腺癌侵袭范围。结果：DWI 提供了前列腺癌可疑癌灶的定位信息，DWI多呈高信号，ADC图为低信号；MRS显示胆碱类化合物(Cho)峰值明显增高，枸橼酸盐(Cit)峰值减低，有助于提高癌灶检出率。结论：DWI和MRS能够无创性地活体评价前列腺癌的侵袭性，两种检查方法联合应用有助于提高癌灶检出率。

    【关键词】前列腺癌；磁共振；DWI；MRS

    【Abstract】 Objective：To investigate the detection rate and clinical significance of combined application of diffusion weighted imaging(DWI)and magnetic resonance spectroscopy(MRS)in prostate cancer.Methods：DWI and MRS findings of 120 patients with prostate carcinoma confirmed by pathology were retrospectively analyzed to locate the invasion range of prostate cancer.Results：DWI provided the location information of suspicious prostate cancer tumor；it showed high signal on diffusion weighted imaging and low signal on ADC maps.MRS showed choline compounds(Cho)peak was significantly increased ......