核工业四一六医院 四川成都 610000

    【摘 要】目的：探讨晚期食道癌患者经紫杉醇联合顺铂化疗临床疗效。方法：对照组给予顺铂联合5-氟尿嘧啶化疗，研究组给予顺铂联合紫杉醇化疗。记录两组晚期食管癌患者临床疗效、化疗相关不良反应发生情况。结果：两组晚期食道癌患者经上述相应方案完成化疗后，研究组总有效率(75.56%)显著高于对照组(55.56%)(P<0.05)；研究组化疗相关不良反应发生情况与对照组对比并无显著差异(P>0.05)。结论：对晚期食管癌患者给予紫杉醇联合顺铂化疗可显著提高其临床疗效，有利于保障患者生活质量及生命安全。

    【关键词】晚期食道癌；紫杉醇联合顺铂化疗；临床疗效

    [Abstract] objective：To investigate the clinical efficacy of paclitaxel combined with cisplatin chemotherapy in patients with advanced esophageal cancer.method：The control group was treated with cisplatin combined with 5- chemotherapy. The study group was treated with cisplatin plus paclitaxel. The clinical effect and adverse reaction of chemotherapy related adverse reactions were recorded in two groups of patients with advanced esophageal cancer.result：Two groups of patients with advanced esophageal cancer by the corresponding program after the completion of chemotherapy and research group ......