硝苯地平联合缬沙坦对老年原发性高血压的治疗效果观察(1)
【摘 要】目的：观察硝苯地平联合缬沙坦对老年原发性高血压的治疗效果。方法：选取2014年2月至2015年2月期间我院收治的原发性高血压老年患者67例作为研究对象，根据治疗的药物不同将其分为单一组(n=30)和联合组(n=37)，单一组应用硝苯地平治疗，联合组在单一组的基础上联合缬沙坦治疗，比较两组患者的治疗效果。结果：单一组的总有效率73%低于联合组的总有效率92%，两组比较，差异有统计学意义，P<0.05。治疗前，两组患者的收缩压、舒张压比较，差异无统计学意义，P>0.05，治疗后，联合组患者的收缩压、舒张压变化优于对照组，差异有统计学意义，P<0.05。结论：硝苯地平联合缬沙坦对老年原发性高血压的治疗明显，能有效地改善患者的收缩压和舒张压变化，值得临床上广泛推广应用。
【关键词】硝苯地平；缬沙坦；老年；原发性高血压；疗效
Effect of nifedipine combined with valsartan in the treatment of essential hypertension in the elderly
Wang Xiuhua Jiao Guihua Li Chunhua
Ji'nan First People's Hospital， Ji'nan， Shandong 250000
[Abstract] Objective： To investigate the effect of nifedipine combined with valsartan in elderly patients with essential hypertension. Methods： 67 cases of elderly patients with essential hypertension admitted in our hospital during February 2014 to February 2015 were selected as the research object and divided into a single group and a combination group according to the different drug treatment. The single group (n=30) was treated with nifedipine and the combination group (n=37)， on the basis of the single group treatment， was treated with valsartan. Therapeutic effect was compared between the two groups of patients. Results： Total efficiency in the single group (73%) was lower than that in the combination group (92%). The difference was statistically significant， P<0.05. Before treatment， the systolic and diastolic blood pressure of the two groups had no significant difference， P>0.05. After treatment， the systolic pressure and diastolic change in the combined group was greater than that in the control group and the difference was statistically significant， P<0.05. Conclusion： The treatment of nifedipine combined with valsartan for hypertension in the elder patients has good clinical efficacy. It can effectively improve the patient's systolic and diastolic blood pressure and it is worthy of further clinical application.
[key words]Nifedipine； Valsartan； Elderly； Hypertension； Curative effect
原发性高血压是临床上常见的一种心血管疾病，是由某些先天性遗传基因与多种因素相互作用而引起的多因素疾病[1]。随着社会经济的发展，人们生活水平的提高，高血压的发病率也呈现上升趋势，对患者的生活质量造成严重的影响[2]。本次研究共选取67例原发性高血压患者作为研究对象，观察应用硝苯地平联合缬沙坦对老年原发性高血压的治疗效果，现总结如下。
1 资料与方法
1.1 一般资料
选取2014年2月至2015年2月期间我院收治的原发性高血压老年患者67例作为研究对象，根据治疗的药物不同将其分为单一组(n=30)和联合组(n=37)，单一组中男性患者22例，女性患者8例，年龄在50～76岁之间，平均年龄在(63.4±2.8)岁，联合组中男性患者25例，女性患者12例，年龄在48～71岁之间，平均年龄在(60.2±2.1)岁，所有患者均符合高血压的诊断标准，没有严重的心、肝、肾等疾病，两组患者的性别、年龄等基本临床资料比较，差异无统计学意义，P>0.05。
1.2 治疗方法, 百拇医药(王秀花 焦桂华 李春华)
【关键词】硝苯地平；缬沙坦；老年；原发性高血压；疗效
Effect of nifedipine combined with valsartan in the treatment of essential hypertension in the elderly
Wang Xiuhua Jiao Guihua Li Chunhua
Ji'nan First People's Hospital， Ji'nan， Shandong 250000
[Abstract] Objective： To investigate the effect of nifedipine combined with valsartan in elderly patients with essential hypertension. Methods： 67 cases of elderly patients with essential hypertension admitted in our hospital during February 2014 to February 2015 were selected as the research object and divided into a single group and a combination group according to the different drug treatment. The single group (n=30) was treated with nifedipine and the combination group (n=37)， on the basis of the single group treatment， was treated with valsartan. Therapeutic effect was compared between the two groups of patients. Results： Total efficiency in the single group (73%) was lower than that in the combination group (92%). The difference was statistically significant， P<0.05. Before treatment， the systolic and diastolic blood pressure of the two groups had no significant difference， P>0.05. After treatment， the systolic pressure and diastolic change in the combined group was greater than that in the control group and the difference was statistically significant， P<0.05. Conclusion： The treatment of nifedipine combined with valsartan for hypertension in the elder patients has good clinical efficacy. It can effectively improve the patient's systolic and diastolic blood pressure and it is worthy of further clinical application.
[key words]Nifedipine； Valsartan； Elderly； Hypertension； Curative effect
原发性高血压是临床上常见的一种心血管疾病，是由某些先天性遗传基因与多种因素相互作用而引起的多因素疾病[1]。随着社会经济的发展，人们生活水平的提高，高血压的发病率也呈现上升趋势，对患者的生活质量造成严重的影响[2]。本次研究共选取67例原发性高血压患者作为研究对象，观察应用硝苯地平联合缬沙坦对老年原发性高血压的治疗效果，现总结如下。
1 资料与方法
1.1 一般资料
选取2014年2月至2015年2月期间我院收治的原发性高血压老年患者67例作为研究对象，根据治疗的药物不同将其分为单一组(n=30)和联合组(n=37)，单一组中男性患者22例，女性患者8例，年龄在50～76岁之间，平均年龄在(63.4±2.8)岁，联合组中男性患者25例，女性患者12例，年龄在48～71岁之间，平均年龄在(60.2±2.1)岁，所有患者均符合高血压的诊断标准，没有严重的心、肝、肾等疾病，两组患者的性别、年龄等基本临床资料比较，差异无统计学意义，P>0.05。
1.2 治疗方法, 百拇医药(王秀花 焦桂华 李春华)