氟哌噻吨治疗伴焦虑抑郁症的浅表糜烂性胃炎患者124例分析(1)
【摘 要】目的：研究氟哌噻吨治疗伴焦虑抑郁症浅表性糜烂性胃炎患者的疗效。方法：选本院124例浅表糜烂胃炎患者，将患者随机分为对照组(n=64)和观察组(n=64)，对照组采用常规质子泵抑制剂治疗，观察组加用氟哌噻吨治疗，对比临床效果。结果：对照组患者临床症状改善不明显，焦虑抑郁状况未得到明显的改善(P>0.05);观察组患者临床症状改善明显，焦虑抑郁状况也得到明显改善(P<0.05)。结论：对于经过正规治疗的慢性浅表性胃炎的患者，治疗效果不明显，并且反复发作，应该考虑患者胃部存在功能性疾病并进行焦虑抑郁调查，并以此为根据进行抗焦虑抑郁治疗，会取得较好的治疗的效果。
【关键词】氟哌噻吨;焦虑抑郁症;浅表性胃炎
Analysis of 124 cases of superficial erosive gastritis treated with flupentixol in patients with anxiety and depression
Fan Jinyun
Department of Gastroenterology， Linyi Mental Health Center， Linyi， Shandong 276005
[Abstract] Objective：To study the efficacy of flupentixol in the treatment of patients with superficial erosive gastritis with anxiety and depression. Methods： 124 patients with superficial sputum gastritis in our hospital were selected. The patients were randomly divided into control group (n=64) and observation group (n=64). The control group was treated with conventional proton pump inhibitor， and the observation group was treated with flupentixol. The clinical effect was compared. Results： The clinical symptoms of the control group were not significantly improved， and the anxiety and depression status were not significantly improved (P>0.05). The clinical symptoms of the observation group were significantly improved， and the anxiety and depression status were also significantly improved (P<0.05). Conclusion： For patients with chronic superficial gastritis who have undergone regular treatment， the treatment effect is not obvious， and repeated attacks should consider the existence of functional diseases in the stomach of the patient and conduct an anxiety and depression investigation， and use this as a basis for anti-anxiety and depression treatment，which will get better treatment results.
[Key words]Flupentixol; Anxiety depression; Superficial gastritis
近年来随着医学模式向生物-心理-社会医学模式转变，在临床治疗中越来越关注患者本身精神状况对患者疾病的影响。人体的胃肠会收到大脑的调节，当外界或人体本身对人体的大脑产生影响，这些影响会随着机体内各种调节机制对胃肠产生影响，造成疾病。随着医学模式的转变，人们在对疾病治疗时扩展了治疗思路，从而产生了新的治疗手段[1-2]。在本次研究中选取了在本院治疗的124例伴焦虑抑郁的慢性浅表性胃炎患者，在临床常规治疗的基础上应用抗焦虑抑郁药物治疗，同时给予患者心理干预治疗，取得了较好的治疗效果，现报道如下。
1 资料与方法
1.1 一般資料
选取2017年1月至12月在本院接受治疗的124例浅表糜烂胃炎的患者，所有患者均接受胃镜检查为浅表糜烂性胃炎，并接受过正规治疗，但是病情反复发作，随机分为对照组(n=64)和观察组(n=64)。所有患者均经过汉密尔顿焦虑和抑郁量表的测定，存在焦虑抑郁情况。排除患者患有其它严重的心，脑，肾等严重疾病的患者，排除具有其它严重心身疾病的患者。对照组患者中男性36例，女性28例，年龄38～67岁，平均年龄(50.34±2.81)岁，病程3～7年，平均病程(4.81±0.34)年;观察组患者中男性38例，女性26例，年龄37～67岁，平均年龄(49.34±1.98)岁，平均病程(4.90±0.51)。对比两组患者基本资料无显著性差异(P>0.05)，具有可比性。
1.2 方法, 百拇医药(范金云)
【关键词】氟哌噻吨;焦虑抑郁症;浅表性胃炎
Analysis of 124 cases of superficial erosive gastritis treated with flupentixol in patients with anxiety and depression
Fan Jinyun
Department of Gastroenterology， Linyi Mental Health Center， Linyi， Shandong 276005
[Abstract] Objective：To study the efficacy of flupentixol in the treatment of patients with superficial erosive gastritis with anxiety and depression. Methods： 124 patients with superficial sputum gastritis in our hospital were selected. The patients were randomly divided into control group (n=64) and observation group (n=64). The control group was treated with conventional proton pump inhibitor， and the observation group was treated with flupentixol. The clinical effect was compared. Results： The clinical symptoms of the control group were not significantly improved， and the anxiety and depression status were not significantly improved (P>0.05). The clinical symptoms of the observation group were significantly improved， and the anxiety and depression status were also significantly improved (P<0.05). Conclusion： For patients with chronic superficial gastritis who have undergone regular treatment， the treatment effect is not obvious， and repeated attacks should consider the existence of functional diseases in the stomach of the patient and conduct an anxiety and depression investigation， and use this as a basis for anti-anxiety and depression treatment，which will get better treatment results.
[Key words]Flupentixol; Anxiety depression; Superficial gastritis
近年来随着医学模式向生物-心理-社会医学模式转变，在临床治疗中越来越关注患者本身精神状况对患者疾病的影响。人体的胃肠会收到大脑的调节，当外界或人体本身对人体的大脑产生影响，这些影响会随着机体内各种调节机制对胃肠产生影响，造成疾病。随着医学模式的转变，人们在对疾病治疗时扩展了治疗思路，从而产生了新的治疗手段[1-2]。在本次研究中选取了在本院治疗的124例伴焦虑抑郁的慢性浅表性胃炎患者，在临床常规治疗的基础上应用抗焦虑抑郁药物治疗，同时给予患者心理干预治疗，取得了较好的治疗效果，现报道如下。
1 资料与方法
1.1 一般資料
选取2017年1月至12月在本院接受治疗的124例浅表糜烂胃炎的患者，所有患者均接受胃镜检查为浅表糜烂性胃炎，并接受过正规治疗，但是病情反复发作，随机分为对照组(n=64)和观察组(n=64)。所有患者均经过汉密尔顿焦虑和抑郁量表的测定，存在焦虑抑郁情况。排除患者患有其它严重的心，脑，肾等严重疾病的患者，排除具有其它严重心身疾病的患者。对照组患者中男性36例，女性28例，年龄38～67岁，平均年龄(50.34±2.81)岁，病程3～7年，平均病程(4.81±0.34)年;观察组患者中男性38例，女性26例，年龄37～67岁，平均年龄(49.34±1.98)岁，平均病程(4.90±0.51)。对比两组患者基本资料无显著性差异(P>0.05)，具有可比性。
1.2 方法, 百拇医药(范金云)
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