红霉素和阿奇霉素序贯疗法对小儿肺炎支原体肺炎的疗效比较(1)
【摘 要】目的：探讨红霉素和阿奇霉素序贯疗法对小儿肺炎支原体肺炎的治疗效果。方法：本次的研究对象为2018年4月至2019年4月在本院接受治疗的90例小儿肺炎支原体肺炎患儿，采用计算机随机匹配分组的方式，将90例患儿分成两组，一组为观察组，另一组为对照组，两组均有45例患儿，对照组使用红霉素对患儿进行治疗，观察组使用阿奇霉素序贯疗法对患儿进行治疗，观察比较两组患儿治疗的总有效率以及患儿肺部啰音的消失时间、咳嗽消失的时间以及患儿的退热时间。结果：观察组患儿治疗的总有效率显著高于对照组患儿治疗的总有效率，两组产生的差异具有统计学意义(P<0.05);观察组患儿肺部啰音的消失时间、咳嗽消失的时间以及退热时间明显低于对照组患儿肺部啰音的消失时间、咳嗽消失的时间以及患儿的退热时间，两组产生的差异具有统计学意义(P<0.05)。结论：相比于红霉素治疗小儿肺炎支原体肺炎，阿奇霉素的治疗效果更加确切，而且治疗的安全性也比较高，缩减患儿临床症状的消失时间，促进患儿的康复，临床效果显著。
【关键词】红霉素;阿奇霉素;肺炎支原体肺炎;治疗
[Abstract] Objective：To study the effect of sequential therapy of erythromycin and azithromycin on the treatment of mycoplasma pneumonia in children. Methods： 90 children with mycoplasmal pneumonia were treated in our hospital from April，2018 to April 2019， and 90 children were divided into two groups， one group was the observation group and the other group was the control group. In the two groups，45 children and the control group were treated with erythromycin. The observation group treated the children with the azithromycin sequential therapy， and observed the total effective rate of the treatment in the two groups and the lung rales of the children. Time to disappear， time to cough and time to get rid of fever. Results： the total effective rate of treatment in the observation group was significantly higher than that in the control group， and the difference between the two groups was statistically significant (P<0.05). The time of disappearance of lung rales， the time of disappearance of cough and the time of fever abatement in the observation group were significantly lower than those in the control group， and the time of disappearance of cough and the time of fever relief were significantly lower in the observation group than in the control group. The difference between the two groups was statistically significant (P<0.05). Conclusion： Azithromycin is more effective than erythromycin in the treatment of mycoplasma pneumoniae pneumonia in children.
[Key words]Erythromycin; Azithromycin; Mycoplasma pneumoniae pneumonia; Treatment
肺炎支原體肺炎属于儿科常见的一种呼吸道疾病，患儿主要临床表现症状为发热、咽痛、咳嗽、咳痰以及胸骨下疼痛等，如果患儿不能得到及时的治疗，则会加重支气管的扩张，进而引发肺间质纤维化、肺不张以及其他重要器官的相关并发症，从而对患儿的生命健康构成严重的威胁。肺炎支原体与细菌、病毒之间存在比较明显的差异，属于一种比较特殊的病原体，临床治疗中一般采用红霉素、阿奇霉素等药物进行治疗，因此，为了能够进一步提高治疗效果，本文作者选择2018年4月至2019年4月在本院接受治疗的90例小儿肺炎支原体肺炎患儿为研究对象，采用计算机随机匹配分组的方式，将90例患儿分成两组，一组为观察组，另一组为对照组，两组均有45例患儿，对照组使用红霉素对患儿进行治疗，观察组使用阿奇霉素序贯疗法对患儿进行治疗，观察比较两组患儿治疗的总有效率以及患儿肺部啰音的消失时间、咳嗽消失的时间以及患儿的退热时间，现报告如下。
1 资料与方法
1.1 一般资料
本次的研究对象为2018年4月至2019年4月在本院接受治疗的90例小儿肺炎支原体肺炎患儿，采用计算机随机匹配分组的方式，将90例患儿分成两组，一组为观察组，另一组为对照组，两组均有45例患儿，两组患儿均确诊为肺炎支原体肺炎，观察组患儿中，男性患儿与女性患儿分别为27例与18例，患儿的年龄为1～11岁;平均年龄为(5.16±1.47)岁，患儿的平均病程为(5.79±3.17)d;对照组患儿中，男性患儿与女性患儿分别为25例与20例，患儿的年龄为1～13岁;平均年龄为(5.94±2.03)岁，患儿的平均病程为(5.61±2.94)d;对比两组患者的一般临床资料，基本上无明显的差异，差异无统计学意义(P>0.05)，可比较。, 百拇医药(连琛琛)
【关键词】红霉素;阿奇霉素;肺炎支原体肺炎;治疗
[Abstract] Objective：To study the effect of sequential therapy of erythromycin and azithromycin on the treatment of mycoplasma pneumonia in children. Methods： 90 children with mycoplasmal pneumonia were treated in our hospital from April，2018 to April 2019， and 90 children were divided into two groups， one group was the observation group and the other group was the control group. In the two groups，45 children and the control group were treated with erythromycin. The observation group treated the children with the azithromycin sequential therapy， and observed the total effective rate of the treatment in the two groups and the lung rales of the children. Time to disappear， time to cough and time to get rid of fever. Results： the total effective rate of treatment in the observation group was significantly higher than that in the control group， and the difference between the two groups was statistically significant (P<0.05). The time of disappearance of lung rales， the time of disappearance of cough and the time of fever abatement in the observation group were significantly lower than those in the control group， and the time of disappearance of cough and the time of fever relief were significantly lower in the observation group than in the control group. The difference between the two groups was statistically significant (P<0.05). Conclusion： Azithromycin is more effective than erythromycin in the treatment of mycoplasma pneumoniae pneumonia in children.
[Key words]Erythromycin; Azithromycin; Mycoplasma pneumoniae pneumonia; Treatment
肺炎支原體肺炎属于儿科常见的一种呼吸道疾病，患儿主要临床表现症状为发热、咽痛、咳嗽、咳痰以及胸骨下疼痛等，如果患儿不能得到及时的治疗，则会加重支气管的扩张，进而引发肺间质纤维化、肺不张以及其他重要器官的相关并发症，从而对患儿的生命健康构成严重的威胁。肺炎支原体与细菌、病毒之间存在比较明显的差异，属于一种比较特殊的病原体，临床治疗中一般采用红霉素、阿奇霉素等药物进行治疗，因此，为了能够进一步提高治疗效果，本文作者选择2018年4月至2019年4月在本院接受治疗的90例小儿肺炎支原体肺炎患儿为研究对象，采用计算机随机匹配分组的方式，将90例患儿分成两组，一组为观察组，另一组为对照组，两组均有45例患儿，对照组使用红霉素对患儿进行治疗，观察组使用阿奇霉素序贯疗法对患儿进行治疗，观察比较两组患儿治疗的总有效率以及患儿肺部啰音的消失时间、咳嗽消失的时间以及患儿的退热时间，现报告如下。
1 资料与方法
1.1 一般资料
本次的研究对象为2018年4月至2019年4月在本院接受治疗的90例小儿肺炎支原体肺炎患儿，采用计算机随机匹配分组的方式，将90例患儿分成两组，一组为观察组，另一组为对照组，两组均有45例患儿，两组患儿均确诊为肺炎支原体肺炎，观察组患儿中，男性患儿与女性患儿分别为27例与18例，患儿的年龄为1～11岁;平均年龄为(5.16±1.47)岁，患儿的平均病程为(5.79±3.17)d;对照组患儿中，男性患儿与女性患儿分别为25例与20例，患儿的年龄为1～13岁;平均年龄为(5.94±2.03)岁，患儿的平均病程为(5.61±2.94)d;对比两组患者的一般临床资料，基本上无明显的差异，差异无统计学意义(P>0.05)，可比较。, 百拇医药(连琛琛)
参见：首页 > 医疗版 > 疾病专题 > 呼吸内科 > 肺炎 > 支原体肺炎