观察干扰素加沙棘籽油栓治疗宫颈炎合并人乳头瘤病毒(HPV)感染的临床疗效(1)
【摘 要】 目的:探究干扰素联合沙棘籽油栓治疗宫颈炎合并人乳头瘤病毒(HPV)感染的效果。方法:选择2016年1月至2019年1月本院30例宫颈炎伴HPV感染患者,根据随机化原则均分成两组,对照组采用干扰素治疗,治疗组采用干扰素+沙棘籽油栓治疗。比较两组治疗效果。结果:治疗组总有效率高于对照组,治疗结束后3个月HPV转阴率高于对照组,有统计学差异(P<0.05);对照组创面愈合及异常分泌物持续时间与治疗组比较,有统计学差异(P<0.05)。结论:干扰素与沙棘籽油栓治疗宫颈炎伴HPV感染效果显著,值得应用。
【关键词】 人乳头瘤病毒感染;沙棘籽油栓;宫颈炎;干扰素
Objective To observe the clinical efficacy of interferon plus seabuckthorn seed oil suppository in the treatment of cervicitis complicated with human papillomavirus (HPV) infection
, 百拇医药
Xiong Kun
Wushan People's Hospital, Chongqing 404700
[Abstract] Objective:To explore the effect of interferon combined with seabuckthorn seed oil suppository in the treatment of cervicitis complicated with human papillomavirus(HPV)infection. Methods: 30 cases of cervicitis with HPV infection in our hospital from January 2016 to January 2019 were randomly divided into two groups.The control group was treated with interferon,and the treatment group was treated with interferon and seabuckthorn seed oil suppository.The therapeutic effects of the two groups were compared. Results: The total effective rate of the treatment group was higher than that of the control group,and the HPV negative conversion rate was higher than that of the control group 3 months after the treatment,with statistical significance(P<0.05);the wound healing and the duration of abnormal secretion in the control group were significantly higher than those in the treatment group(P<0.05). Conclusion: Interferon and Hippophae rhamnoides seed oil suppository in the treatment of cervicitis with HPV infection has significant effect,worthy of promotion.
, 百拇医药
[Key words]Human papillomavirus infection; Seabuckthorn seed oil suppository; Cervicitis; Interferon
慢性宮颈炎是一种十分常见的妇科疾病,常表现为宫颈肥大、宫颈管炎与鳞状上皮化生等。有学者研究指出[1],宫颈炎的发生与HPV感染也存在一定关系。HPV是一种共价双链环状DNA病毒,HPV感染是诱发宫颈癌癌变的重要因素。目前临床主要采用药物治疗宫颈炎伴HPV感染,尤其是局部药物治疗,能有效治疗宫颈糜烂面积较小或炎性分泌物较多的患者,但在治疗宫颈息肉、宫颈腺囊肿与宫颈肥大中效果有限,外加长期使用会导致阴道黏膜受损,因此临床需要寻求一种安全且高效的治疗方法。中医治疗疾病时重视辨证施治与整体观念,有研究显示[2],中医药治疗宫颈炎并HPV感染有效安全,能有效提高机体整体状态与局部内环境,还可降低不良反应,控制宫颈炎复发,提高远期疗效。为进一步提高宫颈炎并HPV感染的临床疗效,现将本院2016年1月至2019年1月30例宫颈炎伴HPV感染患者作为研究对象,探讨干扰素结合沙棘籽油栓治疗的临床价值,汇报如下。
, http://www.100md.com
1 资料与方法
1.1 一般资料
选择30例于本院接受治疗的宫颈炎伴HPV感染患者,样本选取时间为2016年1月至2019年1月,均分成两组,对照组年龄22~46岁,平均(31.25±4.63)岁;病程2~11个月,平均(5.26±2.17)个月;孕次1~3次,平均(2.01±0.43)次。治疗组年龄23~45岁,平均(31.76±4.04)岁;病程2~10个月,平均(5.76±2.09)个月;孕次1~4次,平均(2.06±0.37)次。两组一般资料比较,差异无统计学意义(P>0.05),有可比性。
纳入标准:1)患者病情均确诊,与《实用妇科学》[3]中的诊断标准相符;2)患者能耐受研究采用的药物;3)研究符合医院伦理委员会准则,且患者知情同意。, 百拇医药(熊锟)
【关键词】 人乳头瘤病毒感染;沙棘籽油栓;宫颈炎;干扰素
Objective To observe the clinical efficacy of interferon plus seabuckthorn seed oil suppository in the treatment of cervicitis complicated with human papillomavirus (HPV) infection
, 百拇医药
Xiong Kun
Wushan People's Hospital, Chongqing 404700
[Abstract] Objective:To explore the effect of interferon combined with seabuckthorn seed oil suppository in the treatment of cervicitis complicated with human papillomavirus(HPV)infection. Methods: 30 cases of cervicitis with HPV infection in our hospital from January 2016 to January 2019 were randomly divided into two groups.The control group was treated with interferon,and the treatment group was treated with interferon and seabuckthorn seed oil suppository.The therapeutic effects of the two groups were compared. Results: The total effective rate of the treatment group was higher than that of the control group,and the HPV negative conversion rate was higher than that of the control group 3 months after the treatment,with statistical significance(P<0.05);the wound healing and the duration of abnormal secretion in the control group were significantly higher than those in the treatment group(P<0.05). Conclusion: Interferon and Hippophae rhamnoides seed oil suppository in the treatment of cervicitis with HPV infection has significant effect,worthy of promotion.
, 百拇医药
[Key words]Human papillomavirus infection; Seabuckthorn seed oil suppository; Cervicitis; Interferon
慢性宮颈炎是一种十分常见的妇科疾病,常表现为宫颈肥大、宫颈管炎与鳞状上皮化生等。有学者研究指出[1],宫颈炎的发生与HPV感染也存在一定关系。HPV是一种共价双链环状DNA病毒,HPV感染是诱发宫颈癌癌变的重要因素。目前临床主要采用药物治疗宫颈炎伴HPV感染,尤其是局部药物治疗,能有效治疗宫颈糜烂面积较小或炎性分泌物较多的患者,但在治疗宫颈息肉、宫颈腺囊肿与宫颈肥大中效果有限,外加长期使用会导致阴道黏膜受损,因此临床需要寻求一种安全且高效的治疗方法。中医治疗疾病时重视辨证施治与整体观念,有研究显示[2],中医药治疗宫颈炎并HPV感染有效安全,能有效提高机体整体状态与局部内环境,还可降低不良反应,控制宫颈炎复发,提高远期疗效。为进一步提高宫颈炎并HPV感染的临床疗效,现将本院2016年1月至2019年1月30例宫颈炎伴HPV感染患者作为研究对象,探讨干扰素结合沙棘籽油栓治疗的临床价值,汇报如下。
, http://www.100md.com
1 资料与方法
1.1 一般资料
选择30例于本院接受治疗的宫颈炎伴HPV感染患者,样本选取时间为2016年1月至2019年1月,均分成两组,对照组年龄22~46岁,平均(31.25±4.63)岁;病程2~11个月,平均(5.26±2.17)个月;孕次1~3次,平均(2.01±0.43)次。治疗组年龄23~45岁,平均(31.76±4.04)岁;病程2~10个月,平均(5.76±2.09)个月;孕次1~4次,平均(2.06±0.37)次。两组一般资料比较,差异无统计学意义(P>0.05),有可比性。
纳入标准:1)患者病情均确诊,与《实用妇科学》[3]中的诊断标准相符;2)患者能耐受研究采用的药物;3)研究符合医院伦理委员会准则,且患者知情同意。, 百拇医药(熊锟)