甲硝唑片联合苦参凝胶治疗细菌性阴道炎的临床疗效分析(1)
【摘要】目的：分析甲硝唑片联合苦参凝胶治疗细菌性阴道炎的临床疗效。方法：选取2018年1月～2020年1月232例医院收治细菌性阴道炎患者，随机分为两组。对照组仅采取甲硝唑片治疗，观察组则在对照组基础上加入苦参凝胶治疗，比较两组患者在临床疗效以及症状缓解时间等方面的差异。结果：观察组与对照组的总治疗有效率分别为94.8%和77.6%，观察组患者的总有效率明显高于对照组(P<0.05);观察组与对照组的白带异常缓解时间为(5.6±1.3)天和(8.6±3.2)天，外阴瘙痒缓解时间为(4.3±1.0)天和(7.6±2.6)天，粘膜充血缓解时间为(6.4±1.6)天和(8.6±2.5)天，观察组各症状缓解时间均明显短于对照组(P<0.05)。结论：甲硝唑片联合苦参凝胶能够进一步提高细菌性阴道炎的临床疗效，从而缓解患者的临床症状，值得推广使用。
【关键词】甲硝唑片;苦参凝胶;细菌性阴道炎
[中图分类号]R711.31 [文献标识码]A [文章编号]2096-5249(2020)15-00-02
[Abstract] Objective： To analyze the clinical efficacy of metronidazole tablets combined with Kushen gel in the treatment of bacterial vaginitis. Methods： From January 2018 to January 2020， 232 hospitalized patients with bacterial vaginitis were randomly divided into two groups. The control group was only treated with metronidazole tablets， and the observation group was added with matrine gel treatment on the basis of the control group. Compare the differences in clinical efficacy and symptom relief time between the two groups. Results： The total effective rates of the observation group and the control group were 94.8% and 77.6%， respectively. The total effective rate of the observation group was significantly higher than that of the control group(P<0.05); the remission time of abnormal leucorrhea in the observation group and the control group was (5.6±1.3)days and (8.6±3.2)days， vulvar itching relief time was(4.3±1.0)days and (7.6±2.6)days， mucosal congestion relief time was (6.4±1.6)days and (8.6±2.5)days In the observation group， each symptom relief time was significantly shorter than that in the control group(P<0.05). Conclusion： Metronidazole tablets combined with Sophora flavescens gel can further improve the clinical efficacy of bacterial vaginitis， thereby alleviating the clinical symptoms of patients， which is worthy of popularization and use.
[Key words] Metronidazole Tablets; Sophora Flavescens Gel; Bacterial Vaginitis
细菌性阴道炎主要是由于阴道内微生物平衡破坏引起的细菌感染，可导致引导分泌物增多且伴随异位、外阴瘙痒等症状[1]。该病常见于育龄期妇女，发病缓慢，主要表现为白带增多、外阴瘙痒等，具有一定的传染性[2]。若不尽早治疗对女性患者的生活质量造成较大的影响。目前临床主要是使用甲硝唑片治疗，具有一定的治疗效果与安全性，但是该药物停药后容易复发[3]。因此需要使用更加有效的治疗方案。苦参凝胶具有抗菌消炎的效果，常用于妇科慢性炎症的临床治疗中，具有较高的安全性。本次主要针对甲硝唑片聯合苦参凝胶的疗效展开分析，报道如下。
1 资料与方法
1.1临床资料 选取2018年1月～2020年1月232例医院收治细菌性阴道炎患者，按照随机数字表法将其均分为对照组、观察组，每组116例。纳入标准：经临床症状、体征、实验室培养确诊为细菌性阴道炎;患者及家属知情。排除标准：对本次研究使用药物过敏以及合并严重肝肾功能不全者。观察组中有男性59例，女性57例;年龄为23～52岁，平均为(36.4±5.6)岁。对照组中有男性60例，女性56例;年龄为25～53岁，平均为(37.2±6.2)岁。一般资料组间比较差异无统计学意义(P>0.05)，可比。, 百拇医药(吕海霞 王爱芬)
【关键词】甲硝唑片;苦参凝胶;细菌性阴道炎
[中图分类号]R711.31 [文献标识码]A [文章编号]2096-5249(2020)15-00-02
[Abstract] Objective： To analyze the clinical efficacy of metronidazole tablets combined with Kushen gel in the treatment of bacterial vaginitis. Methods： From January 2018 to January 2020， 232 hospitalized patients with bacterial vaginitis were randomly divided into two groups. The control group was only treated with metronidazole tablets， and the observation group was added with matrine gel treatment on the basis of the control group. Compare the differences in clinical efficacy and symptom relief time between the two groups. Results： The total effective rates of the observation group and the control group were 94.8% and 77.6%， respectively. The total effective rate of the observation group was significantly higher than that of the control group(P<0.05); the remission time of abnormal leucorrhea in the observation group and the control group was (5.6±1.3)days and (8.6±3.2)days， vulvar itching relief time was(4.3±1.0)days and (7.6±2.6)days， mucosal congestion relief time was (6.4±1.6)days and (8.6±2.5)days In the observation group， each symptom relief time was significantly shorter than that in the control group(P<0.05). Conclusion： Metronidazole tablets combined with Sophora flavescens gel can further improve the clinical efficacy of bacterial vaginitis， thereby alleviating the clinical symptoms of patients， which is worthy of popularization and use.
[Key words] Metronidazole Tablets; Sophora Flavescens Gel; Bacterial Vaginitis
细菌性阴道炎主要是由于阴道内微生物平衡破坏引起的细菌感染，可导致引导分泌物增多且伴随异位、外阴瘙痒等症状[1]。该病常见于育龄期妇女，发病缓慢，主要表现为白带增多、外阴瘙痒等，具有一定的传染性[2]。若不尽早治疗对女性患者的生活质量造成较大的影响。目前临床主要是使用甲硝唑片治疗，具有一定的治疗效果与安全性，但是该药物停药后容易复发[3]。因此需要使用更加有效的治疗方案。苦参凝胶具有抗菌消炎的效果，常用于妇科慢性炎症的临床治疗中，具有较高的安全性。本次主要针对甲硝唑片聯合苦参凝胶的疗效展开分析，报道如下。
1 资料与方法
1.1临床资料 选取2018年1月～2020年1月232例医院收治细菌性阴道炎患者，按照随机数字表法将其均分为对照组、观察组，每组116例。纳入标准：经临床症状、体征、实验室培养确诊为细菌性阴道炎;患者及家属知情。排除标准：对本次研究使用药物过敏以及合并严重肝肾功能不全者。观察组中有男性59例，女性57例;年龄为23～52岁，平均为(36.4±5.6)岁。对照组中有男性60例，女性56例;年龄为25～53岁，平均为(37.2±6.2)岁。一般资料组间比较差异无统计学意义(P>0.05)，可比。, 百拇医药(吕海霞 王爱芬)