《基因进展》.2005年.第4期

　

• Ephrin-A2 reverse signaling negatively regulates neural progenitor proliferation and neurogenesis
• Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity
• The Drosophila ortholog of vertebrate TRPA1 regulates thermotaxis
• Take a TRP to beat the heat
• 'No, really, how do they work?'
• SecM facilitates translocase function of SecA by localizing its biosynthesis
• PR-Set7-dependent methylation of histone H4 Lys 20 functions in repression of gene expression and is essential for mitosis
• Frat is dispensable for canonical Wnt signaling in mammals
• Corepressors selectively control the transcriptional activity of PPAR in adipocytes
• Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibition
• Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
• The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment