《血液学杂志》.2005年.第2期

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• A randomized trial of high-versus conventional-dose cytarabine in consolidation chemotherapy for adult de novo acute myeloid leukemia in fir
• Circulating endothelial cells, von Willebrand factor, interleukin-6, and prognosis in patients with acute coronary syndromes
• The safety and efficacy of recombinant human blood coagulation factor IX in previously untreated patients with severe or moderately severe h
• Occult leptomeningeal NHL: go with the flow
• Early TCR- and TCR- PCR detection of T-cell clonality indicates minimal tumor disease in lymph nodes of cutaneous T-cell lymphoma: diagnosti
• Mortality in sickle cell patients on hydroxyurea therapy
• Both proteasomes and lysosomes degrade the activated erythropoietin receptor
• A polymorphism in the VKORC1 gene is associated wi
• High factor VIII levels in venous thromboembolism show linkage to imprinted loci on chromosomes 5 and 11
• Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4
• Hmgb3 deficiency deregulates proliferation and differentiation of common lymphoid and myeloid progenitors
• Extracellular phosphorylation converts pigment epithelium–derived factor from a neurotrophic to an antiangiogenic factor
• Acquired -thalassemia in association with myelodysplastic syndrome and other hematologic malignancies
• High incidence of occult leptomeningeal disease detected by flow cytometry in newly diagnosed aggressive B-cell lymphomas at risk for centra
• Combination immunotherapy with a CpG oligonucleotide(1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: increased interferon-/–
• Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
• ICAM-1 recycling in endothelial cells: a novel pathway for sustained intracellular delivery and prolonged effects of drugs
• Diamond-Blackfan anemia: a "cultural" diagnosis
• STAT3 regulates NF-B recruitment to the IL-12p40 promoter in dendritic cells
• Association of immune abnormalities with telomere shortening in autosomal-dominant dyskeratosis congenita
• Vascular leukocytes contribute to tumor vascularization
• Role of trans-cellular IL-15 presentation in the activation of NK cell–mediated killing, which leads to enhanced tumor immunosurveillance
• Interleukin-15 induces IL-12 receptor 1 gene expression through PU.1 and IRF 3 by targeting chromatin remodeling
• CD1d-unrestricted human NKT cells release chemokines upon Fas engagement
• Dendritic cell-derived IL-2 production is regulated by IL-15 in humans and in mice
• Selective Rac1 inhibition in dendritic cells diminishes apoptotic cell uptake and cross-presentation in vivo
• Functional defect of regulatory CD4+CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis
• Immunogenicity of Bcl-2 in patients with cancer
• Novel mechanism of G-CSF refractoriness in patients with severe congenital neutropenia
• Soluble factors elaborated by human brain endothelial cells induce the concomitant expansion of purified human BM CD34+CD38– cells and SCID-
• Cord blood CD4+CD25+-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function
• Liver iron measurement by MRI
• Targeting NF-B activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells
• Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance
• Durable remissions with autologous stem cell transplantation for high-risk HIV-associated lymphomas
• Interleukin-15 enhances immune reconstitution after allogeneic bone marrow transplantation
• The more the better
• Sickle cell disease and hydroxyurea: the good, the bad, and the future
• Dendritic cells thrive on Rac1
• Stromal cell–derived factor-1/CXCL12–induced chemotaxis of T cells involves activation of the RasGAP-associated docking protein p62Dok-1
• IL-8 and its CXCR1 and CXCR2 receptors participate in the control of megakaryocytic proliferation, differentiation, and ploidy in myeloid me
• New anticoagulants
• Fatal congenital thrombotic thrombocytopenic purpura with apparent ADAMTS13 inhibitor: in vitro inhibition of ADAMTS13 activity by hemoglobi
• HCV quasispecies evolution: association with progression to end-stage liver disease in hemophiliacs infected with HCV or HCV/HIV
• Deficiency of somatic hypermutation of the antibody light chain is associated with increased frequency of severe respiratory tract infection
• Enforced fucosylation of neonatal CD34+ cells generates selectin ligands that enhance the initial interactions with microvessels but not hom
• A novel therapeutic approach for thrombocytopenia by minibody agonist of the thrombopoietin receptor
• A novel role for STAT1 in regulating murine erythropoiesis: deletion of STAT1 results in overall reduction of erythroid progenitors and alte
• Increased risk of extensive chronic graft-versus-host disease after allogeneic peripheral blood stem cell transplantation using unrelated do
• High-resolution tracking of cell division demonstrates differential effects of TH1 and TH2 cytokines on SCF-dependent human mast cell produc
• Improved survival after unrelated donor bone marrow transplantation in children with primary immunodeficiency using a reduced-intensity cond
• On target for advances in the treatment of childhood acute lymphoblastic leukemia
• Prediction of T-cell reconstitution by assessment of T-cell receptor excision circle before allogeneic hematopoietic stem cell transplantati
• G-CSF receptor mutations mix it up
• Minibodies to maximize platelets
• Human embryonic stem cell–derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoie
• Competitive clonal hematopoiesis in mouse chimeras explained by a stochastic model of stem cell organization
• Evaluation of different methods of leukoreduction of donor platelets to prevent alloimmune platelet refractoriness and induce tolerance in a
• Two-phase culture in Diamond Blackfan anemia: localization of erythroid defect
• Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool(BLyS) that is stored in activated neutrophils:
• The efficiency of transfusing high doses of platelets in hematologic patients with thrombocytopenia: results of a prospective, randomized, o
• Autologous stem cell transplantation for HIV-infected individuals with relapsed lymphomas: no longer an experimental strategy
• Donor-derived IL-15 is critical for acute allogeneic graft-versus-host disease
• Hemoglobin versus ADAMTS13
• The Jab1/COP9 signalosome subcomplex is a downstream mediator of Bcr-Abl kinase activity and facilitates cell-cycle progression
• Quantitative analysis of nucleoside transporter and metabolism gene expression in chronic lymphocytic leukemia(CLL): identification of flud
• The Fanconi anemia core complex associates with chromatin during S phase
• Functional gene expression analysis of clonal plasma cells identifies a unique molecular profile for light chain amyloidosis
• Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model
• Inhibition of Akt increases p27Kip1 levels and induces cell cycle arrest in anaplastic large cell lymphoma
• Distinct gene expression profiles determine molecular treatment response in childhood acute lymphoblastic leukemia
• FLT3 inhibition selectively kills childhood acute lymphoblastic leukemia cells with high levels of FLT3 expression