《实验药学杂志》.2005年.第12期

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• B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil
• Repertoire, diversity, and differentiation of specific CD8 T cells are associated with immune protection against human cytomegalovirus disea
• Importance of integrin LFA-1 deactivation for the generation of immune responses
• Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer
• Interleukin(IL)-4 inhibits IL-10 to promote IL-12 production by dendritic cells
• Identification of eosinophil lineage–committed progenitors in the murine bone marrow
• Shifts in targeting of class switch recombination sites in mice that lack μ switch region tandem repeats or Msh2
• Antiviral T cell responses : phalanx or multipronged attack?
• Indecisive interleukin-4?
• C4BP runs damage control
• Deadly stowaway
• A functional promoter polymorphism in monocyte chemoattractant protein–1 is associated with increased susceptibility to pulmonary tuberculos
• Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b–/–Pdcd1–/– mice
• Mastocytosis in mice expressing human Kit receptor with the activating Asp816Val mutation
• A nonclassical non-V14J18 CD1d-restricted(type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance
• Functionally distinct NKT cell subsets and subtypes
• Tuberculosis in children and adults : two distinct genetic diseases
• A toxic gas eases IBD
• New hope for tumor vaccines
• Carbon monoxide ameliorates chronic murine colitis through a heme oxygenase 1–dependent pathway
• Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death
• Suppression of tumor formation in lymph nodes by L-selectin–mediated natural killer cell recruitment
• E47 is required for V(D)J recombinase activity in common lymphoid progenitors
• Secretory leucoprotease inhibitor binds to NF-B binding sites in monocytes and inhibits p65 binding
• TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis
• Chemokine drives tuberculosis
• How SLPI soothes
• Of Interest in the JCB
• Myeloid and plasmacytoid dendritic cells transfer HIV-1 preferentially to antigen-specific CD4+ T cells
• Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors
• Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis
• C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation
• Properties and protective value of the secondary versus primary T helper type 1 response to airborne Mycobacterium tuberculosis infection in
• A chromosomally integrated bacteriophage in invasive meningococci
• Nonhuman primate models of asthma
• No audible wheezing : nuggets and conundrums from mouse asthma models
• Lymphocytes that can't let go