《核酸研究》.2004年.第Da期

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• IntEnz, the integrated relational enzyme database
• BRENDA, the enzyme database: updates and major new developments
• The Database of Interacting Proteins: 2004 update
• The aMAZE LightBench: a web interface to a relational database of cell
• MetaCyc: a multiorganism database of metabolic pathways and enzymes
• MitoProteome: mitochondrial protein sequence database and annotation s
• MitoP2, an integrated database on mitochondrial proteins in yeast and
• STCDB: Signal Transduction Classification Database
• IntAct: an open source molecular interaction database
• topoSNP: a topographic database of non-synonymous single nucleotide po
• HGVbase: a curated resource describing human DNA variation and phenoty
• Improvements in the HbVar database of human hemoglobin variants and th
• ERGDB: Estrogen Responsive Genes Database
• SNP500Cancer: a public resource for sequence validation and assay deve
• The Centre for Modeling Human Disease Gene Trap resource
• GenePaint.org: an atlas of gene expression patterns in the mouse embry
• EICO(Expression-based Imprint Candidate Organizer): finding disease-r
• CleanEx: a database of heterogeneous gene expression data based on a c
• The mouse Gene Expression Database(GXD): updates and enhancements
• Hembase: browser and genome portal for hematology and erythroid biolog
• NASCArrays: a repository for microarray data generated by NASC’s trans
• The PEPR GeneChip data warehouse, and implementation of a dynamic time
• GELBANK: a database of annotated two-dimensional gel electrophoresis p
• The Peptaibol Database: a database for sequences and structures of nat
• APD: the Antimicrobial Peptide Database
• ANTIMIC: a database of antimicrobial sequences
• ORFDB: an information resource linking scientific content to a high-qu
• GermOnline, a cross-species community knowledgebase on germ cell diffe
• DDBJ in the stream of various biological data
• IMGT/GeneInfo: enhancing V(D)J recombination database accessibility
• ACLAME: A CLAssification of Mobile genetic Elements
• UniProt: the Universal Protein knowledgebase
• PIRSF: family classification system at the Protein Information Resourc
• The microRNA Registry
• DBSubLoc: database of protein subcellular localization
• ProTherm, version 4.0: thermodynamic database for proteins and mutants
• SCOR: Structural Classification of RNA, version 2.0
• AANT: the Amino Acid–Nucleotide Interaction Database
• Genew: the Human Gene Nomenclature Database, 2004 updates
• TOPS: an enhanced database of protein structural topology
• DEG: a database of essential genes
• FREP: a database of functional repeats in mouse cDNAs
• Ensembl 2004
• AluGene: a database of Alu elements incorporated within protein-coding
• PEDE(Pig EST Data Explorer): construction of a database for ESTs deri
• The Mouse SAGE Site: database of public mouse SAGE libraries
• LIFEdb: a database for functional genomics experiments integrating inf
• HUGE: a database for human KIAA proteins, a 2004 update integrating HU
• Human protein reference database as a discovery resource for proteomic
• The UCSC Table Browser data retrieval tool
• Pathbase: a database of mutant mouse pathology
• trome, trEST and trGEN: databases of predicted protein sequences
• RTCGD: retroviral tagged cancer gene database
• The Unified Medical Language System(UMLS): integrating biomedical ter
• The Gene Ontology Annotation(GOA) Database: sharing knowledge in Unip
• The ORFanage: an ORFan database
• The KEGG resource for deciphering the genome
• FusionDB: a database for in-depth analysis of prokaryotic gene fusion
• Génolevures: comparative genomics and molecular evolution of hemiascom
• Saccharomyces Genome Database(SGD) provides tools to identify and ana
• The Mouse Genome Database(MGD): integrating biology with the genome
• GenBank: update
• The Molecular Biology Database Collection: 2004 update
• EDITORIAL
• Database resources of the National Center for Biotechnology Informatio
• MIPS: analysis and annotation of proteins from whole genomes
• Xpro: database of eukaryotic protein-encoding genes
• Islander: a database of integrative islands in prokaryotic genomes, th
• DBTBS: database of transcriptional regulation in Bacillus subtilis and
• EASED: Extended Alternatively Spliced EST Database
• ASD: the Alternative Splicing Database
• The Eukaryotic Promoter Database EPD: the impact of in silico primer e
• DBTSS, DataBase of Transcriptional Start Sites: progress report 2004
• Aptamer Database
• JASPAR: an open-access database for eukaryotic transcription factor bi
• HemoPDB: Hematopoiesis Promoter Database, an information resource of t
• The tmRNA website: reductive evolution of tmRNA in plastids and other
• The European ribosomal RNA database
• The ASTRAL Compendium in 2004
• ArchDB: automated protein loop classification as a tool for structural
• DSDBASE: a consortium of native and modelled disulphide bonds in prote
• The Genomic Threading Database: a comprehensive resource for structura
• DomIns: a web resource for domain insertions in known protein structur
• E-MSD: an integrated data resource for bioinformatics
• IMGT/3Dstructure-DB and IMGT/StructuralQuery, a database and a tool fo
• HOMSTRAD: recent developments of the Homologous Protein Structure Alig
• SCOP database in 2004: refinements integrate structure and sequence fa
• The distribution and query systems of the RCSB Protein Data Bank
• MODBASE, a database of annotated comparative protein structure models,
• 3D-GENOMICS: a database to compare structural and functional annotatio
• The EMBL Nucleotide Sequence Database
• The Pfam protein families database
• Recent improvements to the PROSITE database
• The Catalytic Site Atlas: a resource of catalytic sites and residues i
• THGS: a web-based database of Transmembrane Helices in Genome Sequence
• EyeSite: a semi-automated database of protein families in the eye
• ESTHER, the database of the /?-hydrolase fold superfamily of proteins
• SMART 4.0: towards genomic data integration
• MEROPS: the peptidase database
• KinG: a database of protein kinases in genomes
• The KNOTTIN website and database: a new information system dedicated t
• TrSDB: a proteome database of transcription factors
• RPG: the Ribosomal Protein Gene database
• Update of NUREBASE: nuclear hormone receptor functional genomics
• CryptoDB: the Cryptosporidium genome resource
• ApiEST-DB: analyzing clustered EST data of the apicomplexan parasites
• yMGV: a cross-species expression data mining tool
• GeneDB: a resource for prokaryotic and eukaryotic organisms
• Full-malaria 2004: an enlarged database for comparative studies of ful
• dictyBase: a new Dictyostelium discoideum genome database
• PHYTOPROT: a database of clusters of plant proteins
• FLAGdb++: a database for the functional analysis of the Arabidopsis ge
• TcruziDB: an integrated Trypanosoma cruzi genome resource
• TropGENE-DB, a multi-tropical crop information system
• The TIGR Plant Repeat Databases: a collective resource for the identif
• PlantGDB, plant genome database and analysis tools
• MIPS Arabidopsis thaliana Database(MAtDB): an integrated biological k
• SURFACE: a database of protein surface regions for functional annotati
• The SUPERFAMILY database in 2004: additions and improvements
• The SWISS-MODEL Repository of annotated three-dimensional protein stru
• The Gene Ontology(GO) database and informatics resource
• The CyberCell Database(CCDB): a comprehensive, self-updating, relatio
• VirGen: a comprehensive viral genome resource
• TransportDB: a relational database of cellular membrane transport syst
• MolliGen, a database dedicated to the comparative genomics of Mollicut
• RegulonDB(version 4.0): transcriptional regulation, operon organizati
• GenProtEC: an updated and improved analysis of functions of Escherichi
• coliBASE: an online database for Escherichia coli, Shigella and Salmon
• SCMD: Saccharomyces cerevisiae Morphological Database
• AthaMap: an online resource for in silico transcription factor binding
• BGI-RIS: an integrated information resource and comparative analysis w
• The Rice PIPELINE: a unification tool for plant functional genomics
• Rice Proteome Database based on two-dimensional polyacrylamide gel ele
• MaizeGDB, the community database for maize genetics and genomics
• WormBase: a multi-species resource for nematode biology and genomics
• RNAiDB and PhenoBlast: web tools for genome-wide phenotypic mapping pr
• CADRE: the Central Aspergillus Data REpository
• SGMD: the Soybean Genomics and Microarray Database
• Flytrap, a database documenting a GFP protein-trap insertion screen in
• NEMBASE: a resource for parasitic nematode ESTs
• Nematode.net: a tool for navigating sequences from parasitic and free-
• AppaDB: an AcedB database for the nematode satellite organism Pristion