Growth and trafficking

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     Faulhammer et al. found that Sac1p localized to the ER during exponential growth and was retained there by a direct interaction with an integral ER membrane protein called dolichol phosphate mannose synthase, or Dpm1p. When the researchers transferred these fast growing cells to nutrient-poor media, Sac1p moved to the Golgi within minutes.

    Rbiya S. Tuma

    rabiya@nasw.org

    Frank Faulhammer, Gerlinde Konrad, Ben Brankatschk, Sabina Tahirovic, Andreas Kn?dler, and Peter Mayinger

    J. Cell Biol. 2005 168: 185-191.(The lipid phosphatase Sac1p inhibits tra)

    http://www.100md.com/html/DirDu/2007/02/17/36/76/96.htm