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  2003年
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1期
 
 
05/05/04 Yeast DNA polymerase zeta () is essential for error-free replication past thymine glycol
05/05/04 The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity
05/05/04 The ADAMs family of metalloproteases: multidomain proteins with multiple functions
05/05/04 Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression
05/05/04 Phosphorylation of histone H3 during transcriptional activation depends on promoter structure
05/05/04 Pax is required for recombination of transcribed acetylated, 5' IgH V gene segments
05/05/04 Nitric oxide contributes to induction of innate immune responses to gram-negative bacteria in Drosophila
05/05/04 Multipotent cell lineages in early mouse development depend on SOX function
05/05/04 Fgfr regulates patterning of the pharyngeal region
05/05/04 EGF-CFC proteins are essential coreceptors for the TGF- signals Vg and GDF
05/05/04 Checkpoint activation regulates mutagenic translesion synthesis
05/05/04 A two-cilia model for vertebrate left-right axis specification
05/05/04 A biochemical framework for RNA silencing in plants
2期
 
 
05/05/04 tRNA transfers to the limelight
05/05/04 Translation elongation after assembly of ribosomes on the Cricket paralysis virus internal ribosomal entry site without initiation factors or initiato
05/05/04 The multifaceted C. elegans major sperm protein: an ephrin signaling antagonist in oocyte maturation
05/05/04 The Arabidopsis SRR gene mediates phyB signaling and is required for normal circadian clock function
05/05/04 Tbx is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer
05/05/04 Sonic hedgehog-dependent activation of Gli is essential for embryonic hair follicle development
05/05/04 Senescence aging and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform
05/05/04 Proapoptotic BID is required for myeloid homeostasis and tumor suppression
05/05/04 Genetics of dark skin in mice
05/05/04 Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation
05/05/04 c-MYC apoptotic function is mediated by NRF-1 target genes
05/05/04 An Eph receptor sperm-sensing control mechanism for oocyte meiotic maturation in Caenorhabditis elegans
3期
 
 
05/05/04 The ch-TOGXMAP protein is essential for spindle pole organization in human somatic cells
05/05/04 The bloody fate of endothelial stem cells
05/05/04 Six repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development
05/05/04 SCARECROW is involved in positioning the stem cell niche in the Arabidopsis root meristem
05/05/04 How does calorie How does calorie restriction work? work
05/05/04 Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein Hip1 modulates Fgf signaling during branching morphogenesis of the lu
05/05/04 Ectodermal Wntcatenin signaling is required for the establishment and maintenance of the apical ectodermal ridge
05/05/04 Early-replicating heterochromatin
05/05/04 Combinatorial effects of Flk1 and Tal1 on vascular and hematopoietic development in the mouse
05/05/04 CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals
05/05/04 AFP is a novel negative regulator of ABA signaling that promotes ABI5 protein degradation
05/05/04 A Serrate-expressing signaling center controls Drosophila hematopoiesis
4期
 
 
05/05/04 The transcriptional activity of human Chromosome
05/05/04 SWI/SNF-dependent chromatin remodeling of RNR requires TAFIIs and the general transcription machinery
05/05/04 Structure and function of the PWI motif: a novel nucleic acid-binding domain that facilitates pre-mRNA processing
05/05/04 siRNAs can function as miRNAs
05/05/04 Redox regulation of mammalian heat shock factor 1 is essential for Hsp gene activation and protection from stress
05/05/04 Protein ISGylation modulates the JAK-STAT signaling pathway
05/05/04 Pre-mRNA splicing and human disease
05/05/04 p190RhoGAP can act to inhibit PDGF-induced gliomas in mice: a putative tumor suppressor encoded on human Chromosome
05/05/04 Impact of p loss on reversal and recurrence of conditional Wnt-induced tumorigenesis
05/05/04 Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi
05/05/04 Dynamic regulation of the Ras pathway via proteolysis of the NF1 tumor suppressor