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2005年
2005年
第1期
06-11-14
Plasmacytoid predendritic cells initiate psoriasis through interferon- production
06-11-14
Inhibition of astroglial nuclear factor B reduces inflammation and improves functional recovery after spinal cord injury
06-11-14
Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27Kip1 degradation
06-11-14
Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis
06-11-14
Dendritic cells star in Vancouver
06-11-14
The timing of TCR expression critically influences T cell development and selection
06-11-14
Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling
06-11-14
The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion
06-11-14
TACI and BAFF-R mediate isotype switching in B cells
06-11-14
Positive selection of the peripheral B cell repertoire in gut-associated lymphoid tissues
06-11-14
NKT cells promote antibody-induced joint inflammation by suppressing transforming growth factor 1 production
06-11-14
An antagonist peptide mediates positive selection and CD4 lineage commitment of MHC class II–restricted T cells in the absence of CD4
06-11-14
Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block
06-11-14
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
06-11-14
Differential contributions of central and effector memory T cells to recall responses
第2期
06-11-14
Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity
06-11-14
The neuropeptide neuromedin U promotes inflammation by direct activation of mast cells
06-11-14
A malarial cysteine protease is necessary for Plasmodium sporozoite egress from oocysts
06-11-14
Human CD1-restricted T cell recognition of lipids from pollens
06-11-14
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
06-11-14
CD4–CD8– T cells control intracellular bacterial infections both in vitro and in vivo
06-11-14
Dendritic cell maturation by innate lymphocytes : coordinated stimulation of innate and adaptive immunity
06-11-14
Inborn errors of immunity to infection : the rule rather than the exception
06-11-14
Defective thrombus formation in mice lacking coagulation factor XII
06-11-14
Yellow fever 17D as a vaccine vector for microbial CTL epitopes : protection in a rodent malaria model
06-11-14
NFATc2 and NFATc3 transcription factors play a crucial role in suppression of CD4+ T lymphocytes by CD4+ CD25+ regulatory T cells
06-11-14
Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells
06-11-14
BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma
06-11-14
Cyclical modulation of sphingosine-1-phosphate receptor 1 surface expression during lymphocyte recirculation and relationship to lymphoid or
06-11-14
Reciprocal regulation of airway rejection by the inducible gas-forming enzymes heme oxygenase and nitric oxide synthase
第3期
06-11-14
Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA–peptide tetramers
06-11-14
Organic cation transporter 3 modulates murine basophil functions by controlling intracellular histamine levels
06-11-14
Calcium-sensing soluble adenylyl cyclase mediates TNF signal transduction in human neutrophils
06-11-14
Balancing diversity and tolerance : lessons from patients with systemic lupus erythematosus
06-11-14
DC-STAMP is essential for cell–cell fusion in osteoclasts and foreign body giant cells
06-11-14
Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs
06-11-14
Tim-2 regulates T helper type 2 responses and autoimmunity
06-11-14
Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis
06-11-14
Macrophage fusion : the making of osteoclasts and giant cells
06-11-14
An essential role for c-FLIP in the efficient development of mature T lymphocytes
06-11-14
The adaptor molecules LAT and SLP-76 are specifically targeted by Yersinia to inhibit T cell activation
06-11-14
Plasmacytoid precursor dendritic cells facilitate allogeneic hematopoietic stem cell engraftment
06-11-14
Anti-CD63 antibodies suppress IgE-dependent allergic reactions in vitro and in vivo
06-11-14
Dok-1 and Dok-2 are negative regulators of lipopolysaccharide-induced signaling
06-11-14
Cellular FLICE-inhibitory protein is required for T cell survival and cycling
第4期
06-11-14
XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells
06-11-14
IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel
06-11-14
Possible role of human herpesvirus 8 in the lymphoproliferative disorders in common variable immunodeficiency
06-11-14
Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response
06-11-14
Characterization of the early stages of thymic NKT cell development
06-11-14
IL-4 receptor expression on CD8+ T cells is required for the development of protective memory responses against liver stages of malaria para
06-11-14
Inducible DNA breaks in Ig S regions are dependent on AID and UNG
06-11-14
Regulation of TCR and repertoires by local and long-distance control of variable gene segment chromatin structure
06-11-14
Microsomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells
06-11-14
Private specificities of CD8 T cell responses control patterns of heterologous immunity
06-11-14
On imaging, speed, and the future of lymphocyte signaling
06-11-14
Role of ChemR23 in directing the migration of myeloid and plasmacytoid dendritic cells to lymphoid organs and inflamed skin
06-11-14
T cell receptor engagement by peptide–MHC ligands induces a conformational change in the CD3 complex of thymocytes
06-11-14
Identifying protein–protein interactions in somatic hypermutation
06-11-14
Production of type I interferons : plasmacytoid dendritic cells and beyond
第5期
06-11-14
IL-18 with IL-2 protects against Strongyloides venezuelensis infection by activating mucosal mast cell–dependent type 2 innate immunity
06-11-14
A novel glyco-conjugate vaccine against fungal pathogens
06-11-14
NKG2D function protects the host from tumor initiation
06-11-14
Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor–induced apoptosis
06-11-14
Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation
06-11-14
Osteoclast differentiation independent of the TRANCE–RANK–TRAF6 axis
06-11-14
MT1-matrix metalloproteinase directs arterial wall invasion and neointima formation by vascular smooth muscle cells
06-11-14
A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients
06-11-14
Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects
06-11-14
Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product
06-11-14
Defective B cell tolerance checkpoints in systemic lupus erythematosus
06-11-14
Definition of target antigens for naturally occurring CD4+ CD25+ regulatory T cells
06-11-14
Presence of osteoclast-like multinucleated giant cells in the bone and nonostotic lesions of Langerhans cell histiocytosis
06-11-14
Controlling inflammation : a fat chance
06-11-14
Adhesive mechanisms governing interferon-producing cell recruitment into lymph nodes
第6期
06-11-14
Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I
06-11-14
T cell aging : naive but not young
06-11-14
Identifying genes that regulate bone remodeling as potential therapeutic targets
06-11-14
Vaccinia virus protein A46R targets multiple Toll-like–interleukin-1 receptor adaptors and contributes to virulence
06-11-14
Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors
06-11-14
In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma
06-11-14
Complement receptors regulate differentiation of bone marrow plasma cell precursors expressing transcription factors Blimp-1 and XBP-1
06-11-14
A role for fungal -glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice
06-11-14
Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis
06-11-14
Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus
06-11-14
CD44 is a determinant of inflammatory bone loss
06-11-14
Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon- induction
06-11-14
Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA
06-11-14
Signaling for NKT cell development : the SAP–FynT connection
06-11-14
The nucleocytoplasmic shuttling protein CIZ reduces adult bone mass by inhibiting bone morphogenetic protein–induced bone formation
第7期
06-11-14
TGF-1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
06-11-14
Protection from cytomegalovirus after transplantation is correlated with immediate early 1–specific CD8 T cells
06-11-14
Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor
06-11-14
A role for CCR4 in development of mature circulating cutaneous T helper memory cell populations
06-11-14
IL-1 receptor–associated kinase M is a central regulator of osteoclast differentiation and activation
06-11-14
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion
06-11-14
Natural killer cell education in mice with single or multiple major histocompatibility complex class I molecules
06-11-14
Type I interferon dependence of plasmacytoid dendritic cell activation and migration
06-11-14
Repeated stimulation of CD4 effector T cells can limit their protective function
06-11-14
VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis
06-11-14
Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation
06-11-14
IL-18–induced CD83+CCR7+ NK helper cells
06-11-14
Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma
06-11-14
Developmental regulation of Foxp3 expression during ontogeny
06-11-14
Mutation of the phospholipase C-1–binding site of LAT affects both positive and negative thymocyte selection
第8期
06-11-14
Fat meets the cholinergic antiinflammatory pathway
06-11-14
Deletion of DOCK2, a regulator of the actin cytoskeleton in lymphocytes, suppresses cardiac allograft rejection
06-11-14
T cell–induced hyaluronan production by epithelial cells regulates inflammation
06-11-14
Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers
06-11-14
Among B cell non-Hodgkin's lymphomas, MALT lymphomas express a unique antibody repertoire with frequent rheumatoid factor reactivity
06-11-14
Structural and kinetic basis for heightened immunogenicity of T cell vaccines
06-11-14
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator–activated receptor-
06-11-14
Protection from angiotensin II–mediated vasculotoxic and hypertensive response in mice lacking PI3K
06-11-14
IL-7 receptor signaling is necessary for stage transition in adult B cell development through up-regulation of EBF
06-11-14
Contribution of DNA polymerase to immunoglobulin gene hypermutation in the mouse
06-11-14
Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist
06-11-14
Single cell analysis shows decreasing FoxP3 and TGF1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes
06-11-14
Natural selection drives recurrent formation of activating killer cell immunoglobulin-like receptor and Ly49 from inhibitory homologues
06-11-14
An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells
06-11-14
Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN
第9期
06-11-14
A type I interferon autocrine–paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells
06-11-14
T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer
06-11-14
Identification of proteoglycans as the APRIL-specific binding partners
06-11-14
Antigenic conservation and immunogenicity of the HIV coreceptor binding site
06-11-14
PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis
06-11-14
Sustained expansion of NKT cells and antigen-specific T cells after injection of -galactosyl-ceramide loaded mature dendritic cells in cance
06-11-14
Transplantation of a multipotent cell population from human adipose tissue induces dystrophin expression in the immunocompetent mdx mouse
06-11-14
Density of the Notch ligand Delta1 determines generation of B and T cell precursors from hematopoietic stem cells
06-11-14
The 3' end of the heavy chain constant region locus enhances germline transcription and switch recombination of the four genes
06-11-14
Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109
06-11-14
Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade
06-11-14
The insulin A-chain epitope recognized by human T cells is posttranslationally modified
06-11-14
Suppression of allergic airway inflammation by helminth-induced regulatory T cells
06-11-14
TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand
06-11-14
Differential requirements for the chemokine receptor CCR7 in T cell activation during Listeria monocytogenes infection
第10期
06-11-14
In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses
06-11-14
A cytomegaloviral protein reveals a dual role for STAT2 in IFN- signaling and antiviral responses
06-11-14
Antigen persistence is required throughout the expansion phase of a CD4+ T cell response
06-11-14
Recruitment of latent pools of high-avidity CD8+ T cells to the antitumor immune response
06-11-14
Induction of vascular leakage through release of bradykinin and a novel kinin by cysteine proteinases from Staphylococcus aureus
06-11-14
IB kinase (IKK), but not IKK, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss
06-11-14
The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory T cells in peripheral tolerance
06-11-14
Available carbon source influences the resistance of Neisseria meningitidis against complement
06-11-14
TGF-–dependent CD103 expression by CD8+ T cells promotes selective destruction of the host intestinal epithelium during graft-versus-host di
06-11-14
Impaired early B cell tolerance in patients with rheumatoid arthritis
06-11-14
Gadd45 and Gadd45 are critical for regulating autoimmunity
06-11-14
Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses
06-11-14
Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity
06-11-14
Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-B activation
06-11-14
Fibrinogen and fibronectin binding cooperate for valve infection and invasion in Staphylococcus aureus experimental endocarditis
第11期
06-11-14
Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells
06-11-14
Mimicry of a constitutively active pre–B cell receptor in acute lymphoblastic leukemia cells
06-11-14
SURFIN is a polymorphic antigen expressed on Plasmodium falciparum merozoites and infected erythrocytes
06-11-14
Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size
06-11-14
Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia
06-11-14
Live imaging of effector cell trafficking and autoantigen recognition within the unfolding autoimmune encephalomyelitis lesion
06-11-14
In situ characterization of CD4+ T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance
06-11-14
Recruitment of Gr-1+ monocytes is essential for control of acute toxoplasmosis
06-11-14
Endomucin, a CD34-like sialomucin, marks hematopoietic stem cells throughout development
06-11-14
HIF-1–dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia
06-11-14
Innate NKT lymphocytes confer superior adaptive immunity via tumor-capturing dendritic cells
06-11-14
Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity
06-11-14
Autoantibodies make a U-turn : the toll hypothesis for autoantibody specificity
06-11-14
Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow
06-11-14
Mycobacterium tuberculosis and the host response
第12期
06-11-14
A chromosomally integrated bacteriophage in invasive meningococci
06-11-14
Antiviral T cell responses : phalanx or multipronged attack
06-11-14
Shifts in targeting of class switch recombination sites in mice that lack μ switch region tandem repeats or Msh2
06-11-14
Identification of eosinophil lineage–committed progenitors in the murine bone marrow
06-11-14
B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil
06-11-14
Myeloid and plasmacytoid dendritic cells transfer HIV-1 preferentially to antigen-specific CD4+ T cells
06-11-14
Nonhuman primate models of asthma
06-11-14
Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors
06-11-14
Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer
06-11-14
Importance of integrin LFA-1 deactivation for the generation of immune responses
06-11-14
Repertoire, diversity, and differentiation of specific CD8 T cells are associated with immune protection against human cytomegalovirus disea
06-11-14
No audible wheezing : nuggets and conundrums from mouse asthma models
06-11-14
Secretory leucoprotease inhibitor binds to NF-B binding sites in monocytes and inhibits p65 binding
06-11-14
E47 is required for V(D)J recombinase activity in common lymphoid progenitors
06-11-14
Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis